Jin et al., Cell Signal 2007
:
Inhibition of phosphatidylinositol 3-kinase (PI3K) by LY294002 and by a dominant negative PI3K mutant reduced the expression of Redd1 and activation of HIF-1alpha and Sp1 by CoCl ( 2 ) and HCD
Liao et al., J Biol Chem 2011
(Breast Neoplasms) :
PC4 functions are beyond TSA induced phosphatase release, PI3K mediated Sp1 phosphorylation, and HDAC1/2/mSin3A co-repressor release indicating its role as linker coactivator of Sp1 and the transcriptional machinery