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SOD1 — SP1

Text-mined interactions from Literome

Tanaka et al., Arterioscler Thromb Vasc Biol 2000 : Inducible expression of manganese superoxide dismutase by phorbol 12-myristate 13-acetate is mediated by Sp1 in endothelial cells ... Furthermore, the Mn-SOD promoter was activated either by overexpression of Sp1 or the constitutively activated form of PKCbeta in an Sp1 site dependent manner
Maehara et al., Biochem Biophys Res Commun 2002 : Our findings indicate that Mn-SOD gene expression is repressed by Sp1-HDAC1 complex
Afonso et al., Free Radic Biol Med 2006 : Ectopic Sp1 overexpression markedly increased SOD1-basal promoter activity and partially antagonized the TNF-alpha inhibitory effect
Seo et al., Gene 1996 : Sp1 and C/EBP related factor regulate the transcription of human Cu/Zn SOD gene
Minc et al., J Biol Chem 1999 : The human copper-zinc superoxide dismutase gene ( SOD1 ) proximal promoter is regulated by Sp1 , Egr-1, and WT1 via non-canonical binding sites