Gene interactions and pathways from curated databases and text-mining

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GNRH1 — GPI

Text-mined interactions from Literome

Naor et al., Mol Endocrinol 2007 (MAP Kinase Signaling System) : PGF ( 2alpha ), but not PGI2 or PGE2, reduced GnRH-induction of LHbeta gene expression, but not the alpha-gonadotropin subunit or the FSHbeta subunit genes
Ottlecz et al., Life Sci 1988 : Since PGI2 had no effect to alter LH release by cultured pituitary cells in vitro, it is concluded that PGI2 can act on structures near the 3V to inhibit pulsatile release of LHRH
Miyake et al., Endocrinol Jpn 1984 : The effects of PHI-27 , a peptide of the glucagon-secretion family, on luteinizing hormone ( LH ) release and on LH-releasing hormone (LH-RH)- or estradiol induced LH release were examined in a sequential double chamber perifusion system by perifusing the pituitary alone or in sequence with the mediobasal hypothalamus ( MBH ) from normal female rats in diestrus