◀ Back to CDK2
CDK2 — CNTN2
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Iwanaga et al., Oncogene 2001
(Leukemia-Lymphoma, Adult T-Cell) :
The kinase activation was found to result from
Tax induced expression of genes for cell cycle regulatory molecules including cyclin D2, cyclin E, E2F1, CDK2, CDK4 and CDK6, and Tax induced reduction of
CDK inhibitors p19(INK4d) and p27 ( Kip1 )
Riou et al., Cell Growth Differ 2001
:
The
Tax induced increase in
cyclin dependent kinase 2 activity correlated with the phosphorylation of MyoD
Zhi et al., PLoS Pathog 2011
:
Paradoxically, expression of
Tax in most cells
leads to drastic up-regulation of
cyclin dependent kinase inhibitors, p21 ( CIP1/WAF1 ) and p27 ( KIP1 ), which cause p53-/pRb independent cellular senescence