Gene interactions and pathways from curated databases and text-mining

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EGF — PLG

Text-mined interactions from Literome

Lockwood et al., Am J Obstet Gynecol 2001 : Regulation of plasminogen activator inhibitor 1 expression by interaction of epidermal growth factor with progestin during decidualization of human endometrial stromal cells ... Both transforming growth factor alpha and epidermal growth factor , which act through epidermal growth factor receptor, increased steady-state plasminogen activator inhibitor 1 messenger ribonucleic acid levels several-fold when added with estradiol and medroxyprogesterone acetate ... Taken together, these in vitro and in vivo results indicate that both epidermal growth factor and progesterone receptors are required for maximal plasminogen activator inhibitor 1 expression by human endometrial stromal cells
Grant et al., Invest Ophthalmol Vis Sci 1991 (Diabetic Retinopathy) : The authors examined the effect of insulin-like growth factor 1 (IGF 1), epidermal growth factor (EGF) , and acidic fibroblast growth factor (AFGF) on the synthesis by human retinal endothelial cell ( HREC ) of plasminogen activators ( PA ; tissue-type [ t-PA ] and urokinase-type [ u-PA ] ) and plasminogen activator inhibitor (PAI)
Sundareshan et al., Cancer Commun 1991 (Adenocarcinoma...) : At high seeding density, EGF stimulated an increase in urokinase type plasminogen activator activity, which may have augmented the ability of cells to degrade the extracellular matrix
Allen et al., Cancer Res 1990 (Urinary Bladder Neoplasms) : However, epidermal growth factor increased the degradative activity of logarithmically growing normal urothelial cells in the presence of plasminogen and the activity of confluent cells was increased to an even greater extent
Dubeau et al., Cancer Res 1988 (Urinary Bladder Neoplasms) : Differential regulation of plasminogen activators by epidermal growth factor in normal and neoplastic human urothelium
Helseth et al., J Neurooncol 1988 (Glioma) : Type beta transforming growth factor and epidermal growth factor suppress the plasminogen activator activity in a human glioblastoma cell line
Fisher et al., Mol Cell Biol 1981 : The acceleration of the CPE seen in TPA treated Ad5 infected cells was not caused by TPA induction of the protease plasminogen activator, since the protease inhibitors leupeptin and antipain do not inhibit the earlier onset of this CPE and, in contrast, epidermal growth factor , which induces plasminogen activator in HeLa cells, does not induce an earlier CPE
Tranque et al., Endocrinology 1994 : Differential regulation of astrocyte plasminogen activators by insulin-like growth factor-I and epidermal growth factor
Piquette et al., J Clin Endocrinol Metab 1993 : Epidermal growth factor (EGF) , a paracrine hormone found in the human ovary, increases plasminogen activator (PA) activity and the gene expression of PA and plasminogen activator inhibitor (PAI) in human endothelial cells and human cell lines
Bany et al., Mol Reprod Dev 1998 : The effect of epidermal growth factor (EGF) on the accumulation of plasminogen activator (PA) activity in the medium of cultured rat endometrial stromal cells isolated from uteri sensitized for the decidual cell reaction was examined
Bany et al., Biol Reprod 1998 : Effects of epidermal growth factor and interleukin-1alpha on plasminogen activator secretion and decidualization in rat endometrial stromal cells