Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Spiecker et al., Mol Pharmacol 2002 : We studied the effects of tranilast on nuclear factor-kappaB (NF-kappaB) dependent endothelial cell adhesion molecule expression and transcriptional regulation
Cepinskas et al., J Cell Biol 2003 (Inflammation...) : Furthermore, cross linking of platelet-endothelial cell adhesion molecule-1 ( PECAM-1 ), but not intercellular adhesion molecule-1, reduces human umbilical vein endothelial cell nuclear NFkappaB induced by interleukin 1beta
MacMaster et al., Inflamm Res 2003 (Colitis...) : An inhibitor of IkappaB kinase , BMS-345541, blocks endothelial cell adhesion molecule expression and reduces the severity of dextran sulfate sodium induced colitis in mice
Chatterjee et al., Curr Drug Targets 2008 : Moreover, in human umbilical vein endothelial cells, NF-kappaB has been also shown to regulate this enzyme which, in turn, regulates the gene/protein expression of platelet endothelial cell adhesion molecule , intercellular cell adhesion molecule and angiogenesis