◀ Back to CD4

CD4 — CD46

Text-mined interactions from Literome

Marie et al., Nat Immunol 2002 (Dermatitis, Contact...) : We found that engagement of CD46-1 or CD46-2 differentially affected CD8 ( + ) T cell cytotoxicity, CD4 ( + ) T cell proliferation, interleukin 2 (IL-2) and IL-10 production as well as tyrosine phosphorylation of Vav in T lymphocytes
Kemper et al., Nature 2003 : These CD3/CD46 stimulated IL-10 producing CD4+ cells proliferate strongly, suppress activation of bystander T cells and acquire a memory phenotype
Alford et al., J Immunol 2008 : Activation of human primary CD4 ( + ) T cells in the presence of CD46 cross linking induces the development of a distinct immunomodulatory T cell population characterized by high IL-10/granzyme B production ... In this study, we determined the adhesion protein and chemokine receptor expression pattern on human CD3/CD46 activated peripheral blood CD4 ( + ) T cells