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CCR5 — CCR6
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Ebert et al., J Immunol 2002
:
The increased expression of
CCR5 resulted in enhanced chemotaxis toward the CCR5 ligand macrophage-inflammatory protein-1beta/CCL4, but up-regulation of
CCR6 did not
result in altered chemotactic responsiveness to macrophage-inflammatory protein-3alpha/CCL20, suggesting an alternative function for this receptor
Moreno et al., Hepatology 2005
(Drug-Induced Liver Injury) :
In conclusion,
CCR5 deficiency exacerbates T-cell mediated hepatitis, and
leads to increased levels of
CCR5 ligands and a more pronounced liver mononuclear infiltrate, suggesting that CCR5 expression can modulate severity of immuno mediated liver injury
Pham et al., J Neuroimmunol 2012
(Brain Neoplasms...) :
CCL5,
CCR1 and CCR5 in murine glioblastoma : immune cell infiltration and survival rates are not
dependent on individual expression of either CCR1 or
CCR5