Sipma et al., Br J Pharmacol 1995
:
4. The involvement of calmodulin dependent enzyme activities, protein kinase C or an inhibitory GTP binding protein in the bradykinin induced responses was excluded since a calmodulin inhibitor, calmidazolium, a PKC inhibitor, staurosporine and pertussis toxin, respectively did not affect the decline in the cyclic AMP level
Suzuki et al., J Endocrinol 1995
:
These results suggest that extracellular ATP stimulates phospholipase D in a Ca2+/calmodulin dependent manner in osteoblast-like cells, and that neither PKC activation nor GTP binding protein is involved in this mechanism