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CALM1 — REN

Text-mined interactions from Literome

Yatsu et al., Eur J Pharmacol 2003 : These results suggest that A23187 induced inhibition of renin release is mediated by the activation of calmodulin via an increase in intracellular Ca ( 2+ ) and beta-adrenoceptor stimulated renin release is modulated by intracellular Ca ( 2+ ) mobilization
Kurtz et al., Kidney Int Suppl 1991 (Second Messenger Systems) : Stimulation of cAMP formation by forskolin, inhibition of calmodulin by calmidazolium, and inhibition of Na+/H+ exchange by ethylisopropylamiloride enhanced renin secretion
Hano et al., Am J Hypertens 1990 (Hypertension) : These results indicate that calmodulin and protein kinase C play inhibitory roles in renin release from juxtaglomerular cells
Shiotani et al., Nihon Jinzo Gakkai Shi 1989 (Hypertension) : This result indicates that calmodulin plays an inhibitory role in renin release from juxtaglomerular cells
Shinyama et al., Life Sci 1987 : As W-7 stimulates renin release in vivo, the hypothesis that Ca2+-calmodulin plays an inhibitory role in renin release from the kidney is given added support
Antonipillai et al., Endocrinology 1985 : Role of extra- and intracellular calcium and calmodulin in renin release from rat kidney
Hackenthal et al., Clin Exp Hypertens A 1983 : This conclusion is based on the observation that various inhibitors of calmodulin stimulated renin release and that the calcium dependent inhibition of renin release by angiotensin II was abolished in the presence of these inhibitors
Churchill et al., J Pharmacol Exp Ther 1983 : Provided these stimulatory and inhibitory effects are associated with decreased and increased Ca, respectively, these observations are inconsistent with the hypothesis that the effects of Ca, on renin secretion are mediated by changes in Ca-calmodulin activity, since increases in Ca promote rather than attenuate the binding of trifluoperazine to calmodulin
Schwertschlag et al., Clin Exp Pharmacol Physiol 1983 : Our data suggest a role for calmodulin in mediating the effects of angiotensin II on both renin release and renal vascular resistance
Fray et al., J Physiol 1983 : Possible role of calmodulin in renin secretion from isolated rat kidneys and renal cells : studies with trifluoperazine ... Trifluoperazine, an inhibitor of calmodulin and calmodulin directed secretion, was used to examine a possible role of calmodulin in renin secretion from isolated perfused kidneys and renal cortical cells
Park et al., Am J Physiol 1996 : Inhibition of renin secretion mediated by Ca ( 2+ ) -calmodulin was induced by incubating rat renal cortical slices in K ( + ) -rich depolarizing medium, producing > 50 % inhibition
Kim et al., J Pharmacol Exp Ther 1998 : Possible involvement of reversible phosphorylation and dephosphorylation of myosin light chain ( MLC ) by myosin light chain kinase (MLCK) and protein phosphatases ( PPases ), respectively, in the Ca++-calmodulin dependent inhibition of renin secretion was investigated with the use of putative MLCK inhibitor ML-7 [ 1- ( 5-iodonaphthalene-1-sulfonyl ) -1H-hexahydro-1,4-diazepine ] and PPase type1 (PPase-1) and type 2A ( PPase-2A ) inhibitor calyculin A. ML-7 ( 1 x 10 ( - ) 6 to 3 x 10 ( - ) 5 M ) increased renin secretion in vitro from rat renal cortical slices under `` resting '' conditions in a concentration dependent manner with maximal 2.5-fold stimulation