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IRF3 — TNF
Text-mined interactions from Literome
Bennett et al., Blood 2006
(Inflammation...) :
Thus, knock-down of RAX expression by 80 % using small interfering RNA ( siRNA ) prevents
IFNgamma/tumor necrosis factor alpha (TNFalpha) induced PKR activation and eIF2alpha phosphorylation, IkappaB degradation,
IRF-1 expression, and STAT1 phosphorylation, resulting in enhanced murine embryonic fibroblast (MEF) cell survival
Sweeney et al., Arthritis Rheum 2007
(Arthritis, Rheumatoid) :
Poly ( I-C ), lipopolysaccharide, and
tumor necrosis factor alpha (TNFalpha) activated phosphorylation of IKKepsilon and
IRF-3 in FLS
Paun et al., J Biol Chem 2008
(Newcastle Disease) :
In addition,
IRF-5 regulates
TNFalpha but not type I interferon gene transcription in Newcastle disease virus infected peritoneal macrophages
Wu et al., Hepatology 2009
:
TLR stimulated expression of proinflammatory cytokines [ tumor necrosis factor alpha
(TNF-alpha) , interleukin-6 (IL-6) ], and
activation of
IRF-3 was suppressed after up-regulation of HBV replication in HBV-Met cells