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IGF1 — PGF
Text-mined interactions from Literome
Lou et al., Sci China C Life Sci 2000
:
IGF-I stimulated LHR expression in CL.
PGF ( 2alpha )
inhibited expression of
IGF-IR and LHR
Sirotkin et al., Domest Anim Endocrinol 2009
:
IGF-I stimulated P ( 4 ) ( all concentrations ) and
PGF ( at 100 ng/ml ) but suppressed T ( all concentrations ) and E ( 2 ) ( at 1 and 10 ng/ml ) secretion
Makarevich et al., Anim Reprod Sci 1997
:
On the other hand,
PGF release was significantly ( p < 0.05 )
inhibited by both GH and
IGF-I at all concentrations tested
MacDougall et al., Gen Comp Endocrinol 1998
:
Additional tests showed that
insulin-like growth factor-I (IGF-I) had no effect on the production of either PGE2 or
PGF2alpha by PMFG follicles
Sirotkin et al., J Endocrinol 1998
:
IGF-I ( 10 ng/ml or more )
inhibited androstenedione and
PGF secretion, stimulated testosterone, estradiol, OT and cAMP production, but did not influence progesterone, IGFBP-3 or PGE output in these conditions