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AR — FOXA1

Pathways - manually collected, often from reviews:

• NCI Pathway Database FOXA1 transcription factor network: FOXA1 (FOXA1) → DHT/AR complex (AR) (transcription, activates) Gao et al., Mol Endocrinol 2003*
  Evidence: mutant phenotype, reporter gene, physical interaction, other species
• NCI Pathway Database FOXA1 transcription factor network: DHT/AR/FOXA1 complex (AR-FOXA1) → FOXA1 (FOXA1) (modification, collaborate) Gao et al., Mol Endocrinol 2003*
  Evidence: mutant phenotype, physical interaction, other species
• NCI Pathway Database FOXA1 transcription factor network: DHT/AR/FOXA1 complex (AR-FOXA1) → DHT/AR complex (AR) (modification, collaborate) Gao et al., Mol Endocrinol 2003*
  Evidence: mutant phenotype, physical interaction, other species
• NCI Pathway Database FOXA1 transcription factor network: FOXA1 (FOXA1) → DHT/AR complex (AR) (modification, collaborate) Gao et al., Mol Endocrinol 2003*
  Evidence: mutant phenotype, physical interaction, other species
• NCI Pathway Database FOXA1 transcription factor network: FOXA1 (FOXA1) → DHT/AR complex (AR) (transcription, activates) Gao et al., Mol Endocrinol 2003*
  Evidence: mutant phenotype, reporter gene, physical interaction, other species

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: FOXA1 — AR (physical association, affinity chromatography technology) Gao et al., Mol Endocrinol 2003*
• IRef Biogrid Interaction: FOXA1 — AR (direct interaction, pull down) Gao et al., Mol Endocrinol 2003*
• IRef Dip Interaction: Complex of AR-KMT2D-KMT2A-FOXA1-KDM6A-ASH2L-ERG-ASXL1 (anti bait coimmunoprecipitation) Grasso et al., Nature 2012
• IRef Dip Interaction: AR — FOXA1 (physical association, anti bait coimmunoprecipitation) Grasso et al., Nature 2012
• IRef Hprd Interaction: AR — FOXA1 (in vivo) Gao et al., Mol Endocrinol 2003*
• IRef Hprd Interaction: AR — FOXA1 (in vitro) Gao et al., Mol Endocrinol 2003*
• IRef Intact Interaction: AR — FOXA1 (physical association, anti bait coimmunoprecipitation) Sharma et al., Cancer Cell 2013*
• IRef Ophid Interaction: AR — FOXA1 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005
• IRef Ophid Interaction: AR — FOXA1 (aggregation, confirmational text mining) Gao et al., Mol Endocrinol 2003*

Text-mined interactions from Literome

Lee et al., Biochem Biophys Res Commun 2008 (Prostatic Neoplasms) : Hepatocyte nuclear factor-3 alpha ( HNF-3alpha ) negatively regulates androgen receptor transactivation in prostate cancer cells
Sahu et al., EMBO J 2011 (Prostatic Neoplasms) : Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer