Gene interactions and pathways from curated databases and text-mining

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GPX4 — PTGS2

Text-mined interactions from Literome

Barrière et al., Anticancer Res 2004 (Colonic Neoplasms) : PHGPx overexpression induces an increase in COX-2 activity in colon carcinoma cells
Brigelius-Flohé et al., Biol Chem 2006 : PHGPx specifically interferes with NF-kappaB activation by interleukin-1, reduces leukotriene and prostanoid biosynthesis, prevents COX-2 expression, and is indispensable for sperm maturation and embryogenesis