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BCL2 — FLT3

Text-mined interactions from Literome

Minami et al., Blood 2003 (Leukemia) : In WtFLT3 transfected 32D ( WtFLT3-32D ) cells, FLT3 ligand ( FL ) stimulation did not restore the down-regulation of Bcl-XL but maintained the phosphorylation of Bad ... FLT3 kinase inhibitor, AG1296, alone not only dephosphorylated Bad but also down-regulated Bcl-XL , leading FLT3/ITD-32D cells into apoptosis
Frasca et al., J Leukoc Biol 2010 : Although FLT-3L-DCs were the least effective at inducing CD8 T cell proliferation, FLT-3L-DCs promoted better CD8 T cell survival and increased Bcl-2 and MCL-2 expression in CD8 T cells