Gene interactions and pathways from curated databases and text-mining

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BCL2 — IRF6

Text-mined interactions from Literome

Fortunato et al., Pancreas 2000 : These data show that ( a ) long-term alcohol feeding suppresses apoptosis in the pancreas ; ( b ) LPS increases the rate of apoptosis in the pancreas ; ( c ) caspase-3 activity and Bcl-2 expression change in opposite directions ; ( d ) TUNEL positivity and Fas ligand expression are increased, and Bcl-2 is decreased in ethanol fed + LPS injected rats
Cinel et al., Pharmacol Res 2002 (Endotoxemia...) : In conclusion, 3-AB decreases LPS induced apoptosis in ileum by preventing LPS induced depletion of Bcl-2 and blocking iNOS gene
Liu et al., J Biol Chem 2004 : In response to lipopolysaccharide (LPS) stimulation, BCL10 was recruited to TLR4 signaling complexes and associated with Pellino2, an essential component down-stream of BCL10 in the TLR4 pathway
Sano et al., Res Vet Sci 2005 : By real-time quantitative PCR analysis, it was indicated that Bcl-xL and Bax levels in canine neutrophils were significantly affected by LPS stimulation
Yu et al., FASEB J 2005 (Inflammatory Bowel Diseases) : Western blot showed that LPS in high glucose increased the levels of anti-apoptotic Bcl-2 and Bcl-X ( L, ) and did not change proapoptotic Bax
Ramana et al., Free Radic Biol Med 2007 : In addition, AR inhibition prevented the LPS induced down-regulation of Bcl-xl and up-regulation of Bax and Bak in macrophages
Lee et al., J Pineal Res 2009 (Body Weight...) : In western blot analysis, LPS reduced the levels of Bcl-XL and procaspase-3 in SD mice
Cui et al., Acta Pharmacol Sin 2013 (Atherosclerosis) : In ApoE ( -/- ) mice, administration of amiloride significantly suppressed LPS accelerated atherosclerosis and LPS induced increase of NHE1 activity, and reversed LPS induced down-regulation of Bcl-2 expression