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Text-mined interactions from Literome
Heinzelmann et al., J Immunol 1999
:
In the current study, we hypothesize that HBP is internalized in monocytes via endocytosis, and this internalization is an important mechanism by which
HBP enhances LPS induced
TNF-alpha release
Heinzelmann et al., Int J Surg Investig 2001
:
HBP alone
induced the production of IL-8, macrophage inhibitory protein MIP-1alpha, and
TNF-alpha
Soehnlein et al., J Clin Invest 2008
(Disease Models, Animal...) :
Mechanistically,
HBP and HNP1-3
triggered macrophage release of
TNF-alpha and IFN-gamma, which acted in an autocrine loop to enhance expression of CD32 and CD64 and thereby enhance phagocytosis
Heinzelmann et al., J Immunol 1998
:
Our results demonstrated that
HBP alone ( 10 microg/ml )
stimulated the production of
TNF-alpha from isolated monocytes ... These data suggest that mechanisms other than increased CD14 expression are responsible for the enhanced release of
TNF-alpha or PGE2 in
response to
HBP and LPS
Heinzelmann et al., Infect Immun 1998
:
In addition, fucoidan and EDTA abrogate the enhancing
effect of
HBP on LPS induced
TNF-alpha production