◀ Back to IRF6

IRF6 — PLIN2

Text-mined interactions from Literome

Gu et al., Am J Physiol Endocrinol Metab 2008 : Lipopolysaccharide (LPS) enhanced the ADRP expression in RAW264.7 cells or peritoneal macrophages from wild-type mice, but not in macrophages from TLR4-deficient mice ... Actinomycin D almost completely abolished the LPS effect, whereas cycloheximide decreased the expression at 12 h, indicating that the LPS induced ADRP expression was stimulated at the transcriptional level and was also mediated by new protein synthesis ... LPS enhanced the ADRP promoter activity, in part, by stimulating activator protein (AP)-1 binding to the Ets/AP-1 element
Feingold et al., Atherosclerosis 2010 (Atherosclerosis) : LPS also induced ADRP/ADFP and Mal1 in J774 macrophages and ADRP/ADFP in human monocytes
Xie et al., Cell Physiol Biochem 2011 : Furthermore, DBZ suppressed LPS activated macrophages lipid accumulation, partly due to inhibiting the expression of LPS induced aP2 and ADRP in macrophges
Wang et al., Lipids in health and disease 2012 (Atherosclerosis) : In addition, pre-treatment with anti-Toll-like receptor 4 (TLR4) antibody diminished the LPS induced lipid deposition and ADRP expression