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PDE4A — PRKAR2A
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Laliberté et al., FEBS Lett 2002
:
In vitro
PKA phosphorylation
mediated human
PDE4A4 activation
Millen et al., Eur J Cell Biol 2006
(Anoxia...) :
Despite the hypoxia induced increases in the expression of
PDE4A10/11 , PDE4B2 and PDE4D5 and
activation of certain of these long PDE4 isoforms through
PKA phosphorylation, we suggest that the failure to see any overall increase in PDE4 activity is due to ERK mediated phosphorylation and inhibition of particular PDE4 long isoforms