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ANGPT4 — EPHB2
Text-mined interactions from Literome
Smith et al., Endocrinology 2006
(MAP Kinase Signaling System) :
Stimulation of Ishikawa cells and human endometrial biopsy explants with 100 nm iloprost ( a PGI analog ) rapidly activated
ERK1/2 signaling and
induced the expression of proangiogenic genes, basic fibroblast growth factor,
angiopoietin-1 , and angiopoietin-2, in an epidermal growth factor receptor (EGFR) dependent manner
Clark et al., Neuropeptides 2011
(MAP Kinase Signaling System) :
Moreover, inhibition of the ERK1/2 MAP kinase pathway by 10 µM PD98059 attenuated
Ang III induced
ERK1/2 phosphorylation ... Ang III induction of ERK1/2 occurred via stimulation of the Ang AT(1) receptor since pretreatment with 10 µM Losartan, a selective AT(1) receptor blocker, prevented
Ang III induced
ERK1/2 phosphorylation