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CD1D — CD8A
Text-mined interactions from Literome
Lee et al., Exp Mol Med 2009
:
Although CD4 and
CD8 coreceptors are not directly
involved in the interaction between
CD1d and the T cell receptors ( TCRs ) of iNKT cells, a conspicuous lack of CD8 ( + ) iNKT cells in mice raised the question of whether CD8 ( + ) iNKT cells are excluded due to negative selection during their thymic development, or if there is no lineage commitment for the development of murine CD8 ( + ) iNKT cells
Joshi et al., J Leukoc Biol 2012
:
These results provide a clear demonstration that although
CD1d expression on DCs is
essential for NKT enhanced
CD8 ( + ) T cell expansion, it is dispensable for specific antibody production