Reidy et al., Am J Physiol Endocrinol Metab 2002
:
This study shows that leptin causes a strong activation of TAG/FA cycling , lipolysis, and FA oxidation, shifting fuel preference from carbohydrates to lipids
Solinas et al., FEBS Lett 2004
:
The direct effect of leptin on skeletal muscle thermogenesis is mediated by substrate cycling between de novo lipogenesis and lipid oxidation ... Our results suggest that the direct effect of leptin in stimulating thermogenesis in skeletal muscle is mediated by substrate cycling between de novo lipogenesis and lipid oxidation, and that this cycle requires both PI3K and AMPK signaling
Kochan et al., J Physiol Pharmacol 2006
(Weight Gain...) :
The effects of weight cycling on serum leptin levels and lipogenic enzyme activities in adipose tissue