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CHI3L1 — VEGFA

Text-mined interactions from Literome

Faibish et al., Mol Cancer Ther 2011 (Disease Progression...) : mAY also abolished YKL-40 induced activation of the membrane receptor VEGF receptor 2 ( Flk-1/KDR ) and intracellular signaling mitogen activated protein ( MAP ) kinase extracellular signal regulated kinase ( Erk ) 1 and Erk 2
Francescone et al., J Biol Chem 2011 (Disease Progression...) : Here, we aimed to elucidate the role YKL-40 plays in the regulation of VEGF expression, tumor angiogenesis, and radioresistance ... YKL-40 up-regulated VEGF expression in glioblastoma cell line U87, and both YKL-40 and VEGF synergistically promote endothelial cell angiogenesis ... Interestingly, long term inhibition of VEGF up-regulated YKL-40