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VEGFA — XRCC6
Text-mined interactions from Literome
Gama et al., Cell Death Differ 2009
:
We found that
VEGF inhibited cytosolic
Ku70 degradation induced by apoptotic stress ... We found that
VEGF stimulated nuclear translocation of Hdm2 in EC and efficiently
inhibited Ku70 degradation
Tawa et al., Circ Res 2010
(Disease Models, Animal...) :
These results demonstrate a novel molecular mechanism by which
Rap1 and afadin
regulate the
VEGF- and S1P induced angiogenesis
Lakshmikanthan et al., Blood 2011
:
Using ECs obtained from Rap1-deficient mice we demonstrate that
Rap1b promotes
VEGF-VEGFR2 kinase activation and regulates integrin activation ... Importantly, the
Rap1b dependent
VEGF-VEGFR2 activation is in part mediated via integrin a ( v ) ß ( 3 ) ... These results provide a novel insight into the
role of
Rap1 in
VEGF signaling in ECs
Li et al., J Huazhong Univ Sci Technolog Med Sci 2011
:
VEGF stimulated
Rap1 activity, phosphorylation of ERK and Akt, cyclin D1 expression and cell proliferation were repressed in HUVECs overexpressing Rap1GAP as compared to empty vector transfected control