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CDKN1A — RRM2B
Text-mined interactions from Literome
Devlin et al., Mol Cancer Res 2008
(Prostatic Neoplasms) :
Silencing
p53R2 also
reduced the levels of
p21 ( WAF1/CIP1 ) at the posttranscriptional level, suggesting links between the p53 dependent DNA repair and cell cycle arrest pathways
Zhang et al., Mol Cancer Ther 2011
(Neoplasms) :
Conversely, overexpression of
p53R2-GFP resulted in an increase in the expression of
p21 and decrease in the expression of cyclin D1, which correlated with reduced cell population in S-phase in vitro and suppressed growth in vivo