Gene interactions and pathways from curated databases and text-mining

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ESR1 — SOCS3

Text-mined interactions from Literome

Matthews et al., Biochem Biophys Res Commun 2005 (Breast Neoplasms) : Estrogen receptor-alpha regulates SOCS-3 expression in human breast cancer cells ... In summary, this study shows that ERalpha directly regulates human SOCS-3 promoter activity in human breast cancer cells, thus modulating cytokine activity
Seifert et al., Int J Oncol 2009 (Breast Neoplasms) : This increase resulted in transactivation of ERalpha and induction of ERalpha mediated transcription of Hdm2 and SOCS3