Doi et al., Arch Biochem Biophys 2009
:
AT-III markedly attenuated the ADP induced phosphorylation levels of p44/p42 MAPK and p38 MAPK
Sun et al., Chin Med J (Engl) 2009
(Acute Lung Injury) :
AT-III without concomitant heparin inhibited the activation of ERK1/2 and P38 MAPK , down-regulated the levels of downstream cytokines TNF-alpha and IL-6, relieved endothelial permeability, and improved the ALI in endotoxin induced rats