Gene interactions and pathways from curated databases and text-mining

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FYN — LHCGR

Text-mined interactions from Literome

Mizutani et al., Mol Endocrinol 2006 (Leydig Cell Tumor...) : Moreover, activation of the LHR in MA-10 cells results in the stimulation of the activity of Fyn and Yes, and overexpression of either of these two tyrosine kinases enhances the LHR mediated phosphorylation of FAK-Tyr576
Shiraishi et al., Exp Cell Res 2008 : Transfection of interfering constructs shows that the LHR mediated activation of Fyn in MA-10 cells is necessary for the phosphorylation of the EGFR and ERK1/2 in I-10 cells
Galet et al., Cell Signal 2008 : Arrestin-3 is essential for the activation of Fyn by the luteinizing hormone receptor (LHR) in MA-10 cells ... Expression of the siRNA against Galpha ( s ) decreased the level of Galpha ( s ) and LHR stimulated cAMP production by approximately 50 % but did not affect LHR stimulated Fyn activation or FAK phosphorylation ... Likewise, expression of the siRNA against Galpha(11) decreased the level of Galpha(11) and LHR stimulated inositol phosphate production by approximately 50 % but did not affect LHR stimulated Fyn activation or FAK phosphorylation