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GRAP2 — IL17A

Text-mined interactions from Literome

Sylvester et al., Cell Signal 2004 : IL-17 stimulated phosphorylation of extracellular signal regulated kinase ( ERK ), protein 38 (p38) and c-Jun N-terminal kinase (JNK)
Wuyts et al., J Heart Lung Transplant 2005 : We found that IL-17 induces activation of p38MAPK , JNK and p42/p44ERK in HASMC
Paradowska et al., Arch Immunol Ther Exp (Warsz) 2007 (Arthritis, Rheumatoid) : IL-17 binding to an IL-17 receptor expressed on epithelial, endothelial, and fibroblastic stromal cells triggers the activation of transcription factor NF-kappaB and mitogen activated protein kinase ( p-38 ), which in turn results in the secretion of IL-1, TNF-alpha, IL-6, IL-8, or prostaglandin E2
Chen et al., Molecular vision 2011 : Inhibition of p38MAPK , phosphoinositide 3-kinase (PI3K)-Akt and nuclear factor-kappaB ( NF-?B ), with the inhibitors SB203580, LY294002 and pyrrolydine dithiocarbamate ( PDTC ) respectively, reduced IL-17 ( 100 ng/ml ) mediated production of CXCL8, CCL2, and IL-6 in a concentration dependent manner
Mellett et al., Nature communications 2012 : Neutrophil recruitment, in response to in vivo administration of interleukin-17A, is abolished in interleukin-17 receptor D-deficient mice, correlating with reduced interleukin-17A induced activation of p38 mitogen activated protein kinase and expression of the neutrophil chemokine MIP-2