UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

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CAST — PXN

Pathways - manually collected, often from reviews:

BioCarta mcalpain and friends in cell motility: Calpastatin (CAST) → Paxillin/FAK/Talin/Actin/Integrin-alpha/Integrin-beta/ECM complex (PXN-PTK2-TLN1-ACTA1-ITGA1-ITGB1) (modification, inhibits)
BioCarta mcalpain and friends in cell motility: Calpastatin (CAST) → Paxillin/FAK/Talin/Actin/Integrin-alpha/Integrin-beta/ECM complex (PXN-PTK2-TLN1-ACTA1-ITGA1-ITGB1) (modification, inhibits)
BioCarta mcalpain and friends in cell motility: Paxillin/FAK/Talin/MLC(+)/Integrin-alpha/Integrin-beta/ECM complex (PXN-PTK2-TLN1-MLC1-ITGA1-ITGB1) → Calpastatin (CAST) (modification, collaborate)