Gene interactions and pathways from curated databases and text-mining

◀ Back to INS

GAST — INS

Text-mined interactions from Literome

Sjöholm et al., Pancreas 2000 : Gastrin , expressed in islets during fetal life, did not affect basal or glucose stimulated insulin release, or insulin content, in islets maintained in either low or high glucose
Robbins et al., Am J Surg 1976 (Gastritis...) : No significant changes were seen in insulin stimulated acid secretion, insulin stimulated pepsin secretion, antral gastrin levels, or G cell numbers
Madaus et al., Neuropeptides 1991 : The effect of glucose and insulin on vagally induced gastrin , bombesin-like immunoreactivity and somatostatin secretion from the perfused rat stomach
Roche et al., FEBS Lett 1991 : The effects of Pertussis toxin ( PTx ) and extracellular Ca2+ were investigated on gastrin induced Ins ( 1,4,5 ) P3 mass level in isolated gastric parietal cells
Rehfeld et al., Acta Physiol (Oxf) 2011 : Therefore, exogenous gastrin and CCK peptides stimulate insulin and glucagon secretion in man
Zhao et al., Peptides 2011 : Sulfated gastrin stimulates ghrelin and growth hormone release but inhibits insulin secretion in cattle
Simoens et al., Gastroenterology 1989 : Insulin and bombesin induced considerable gastrin release in omeprazole treated dogs, but plasma gastrin concentrations returned almost to basal values after 3 h. Omeprazole administered alone had no significant effect on basal gastrin levels
Olsen et al., Gut 1987 : Pl-gastrin was significantly decreased during infusion of 10 pmol/kg/h of SMS 201-995 and insulin was significantly inhibited during infusion of 50 pmol/kg/h. SMS 201-995 in a dose of 50 pmol/kg/h inhibited basal and submaximal pentagastrin stimulated acid secretion by 77 % and 84 % respectively ( p less than 0.01 )
Verspohl et al., Naunyn Schmiedebergs Arch Pharmacol 1986 : Its inhibitory effect presumably is not a gastrin antagonizing effect since gastrin does not stimulate insulin secretion
Starosel'tseva et al., Probl Endokrinol (Mosk) 1988 (Chronic Disease...) : [ The role of gastrin in regulating insulin and glucagon secretion in patients with diabetes mellitus ]
Barros D'sa et al., Gut 1978 : Somatostatin inhibited the gastrin response to insulin and food
Greco et al., Acta Hepatogastroenterol (Stuttg) 1979 (Hypoglycemia...) : Gastrin response to insulin in patients with cirrhosis of the liver
Service et al., J Clin Endocrinol Metab 1978 : Direct effect of insulin on secretion of insulin, glucagon, gastric inhibitory polypeptide, and gastrin during maintenance of normoglycemia ... The direct effect of insulin on the secretion of insulin ( as measured by C-peptide ), glucagon, gastric inhibitory polypeptide, and gastrin was studied in normal subjects by infusing insulin while the plasma level of glucose was maintained in the normal fasting range ( euglycemic clamp )
Watanabe et al., Nihon Geka Gakkai Zasshi 1985 (Duodenal Ulcer) : Integrated gastrin response to meat extract and insulin hypoglycemia stimulation was also increased significantly six months postoperatively
Tkaczewski et al., Acta Hepatogastroenterol (Stuttg) 1979 (Duodenal Ulcer...) : It is suggested that the different effect of glucagon on gastrin levels may be due to gastrin-insulin interaction ; the levels of the two hormones in the blood of duodenal patients were higher than in the other two groups studied
Vaysse et al., Endocrinology 1981 : S14 and S28 inhibited the release of gastrin, insulin, and glucagon ; insulin release was inhibited most effectively, with glucagon release next, and gastrin release least inhibited
Tokunaga et al., Gastroenterol Jpn 1984 : However, the specific gastrin binding was not inhibited by glucagon, insulin , acetylcholine, atropine, histamine, or cimetidine
Debas et al., Surgery 1984 : AV abolished the plasma gastrin response to insulin but had no effect on either basal or meal stimulated gastrin release
Grabner et al., Scand J Gastroenterol 1984 : Furthermore it seems that the adrenergic fibers in the vagus nerve might have some modulating effect on the insulin induced gastrin release
Grabner et al., Scand J Gastroenterol 1981 : Insulin stimulated ( 0.15 IU/kg ) gastric acid and pepsin output and serum gastrin were measured before and after beta-adrenergic blockade with propranolol ( 20 microgram/kg/min intravenous infusion ) in gastric fistula and Heidenhain pouch dogs ... However, the insulin induced gastrin release was unaltered by intravenous infusion of propranolol
Emås et al., Surgery 1980 (Duodenal Ulcer...) : In another preoperative and postoperative test on each patient, the serum gastrin test, the serum gastrin response ( radioimmunoassay ) to insulin was determined during gastric perfusion with citrate-phosphate buffer pH 7.0 ... Before operation the integrated serum gastrin response to insulin was significant ( P less than 0.01 )
Jensen et al., Am J Physiol 1980 : The effects of the four main forms of gastrin ( component I, gastrin-34, gastrin-17, and gastrin-14 ) on insulin , glucagon, and exocrine secretion were measured on the isolated perfused porcine pancreas
Ahrén et al., Diabetologia 1981 : Effects of vasoactive intestinal polypeptide (VIP), secretin and gastrin on insulin secretion in the mouse ... The in vivo effects of vasoactive intestinal polypeptide (VIP), secretin and two different molecular forms of gastrin , gastrin 17 and pentagastrin, on basal and stimulated insulin secretion have been investigated in the mouse ... Gastrin 17 and pentagastrin did not affect glucose- or carbachol induced insulin release, whereas they inhibited L-IPNA induced insulin secretion
Verga et al., Archivio per le scienze mediche 1980 : The data suggest that any participation of gastrin in the regulation of insulin secretion following a glucose meal can be excluded
Schrumpf et al., Scand J Gastroenterol 1981 (Hypoglycemia...) : Fasting, meal stimulated, and insulin-hypoglycemia stimulated serum gastrin levels were measured before and 3 and 12 months after gastric bypass surgery in nine obese patients
Watanabe et al., Gastroenterol Jpn 1980 (Duodenal Ulcer) : Integrated gastrin response ( IGR ) to meat extract and insulin hypoglycemia stimulation was also increased significantly ( p < 0.01 ) six months postoperatively
Brandsborg et al., Scand J Gastroenterol 1977 (Duodenal Ulcer) : The effect of insulin on food stimulated secretion of gastrin after parietal cell vagotomy and selective gastric vagotomy
Fluckey et al., J Gerontol A Biol Sci Med Sci 1996 : These data suggest that following resistance exercise, insulin increased rates of protein synthesis in both soleus and GAST regardless of age, and it appeared that this insulin mediated elevation may have occurred at the level of translation
Shiratori et al., Tohoku J Exp Med 1977 : ( 3 ) The serum gastrin response to insulin was highly increased after SPV and TV, whereas the response was slightly increased and decreased after SV and SAV, respectively
Lam et al., Digestion 1976 (Duodenal Ulcer...) : In 60 uncomplicated duodenal ulcers ( DU ), maximum acid output ( MAO ) and acid output following insulin hypoglycaemia ( IAO ) were measured, and in 30 patients also the serum gastrin responses to insulin and to standard meals, In 7 normal controls, all 4 items were measured