◀ Back to CCL11
CCL11 — RELA
Text-mined interactions from Literome
Clarke et al., J Immunol 2008
:
In this study, we describe a novel role for protein kinase C ( PKC ) betaIotaIota in augmenting
NF-kappaB mediated TNF-alpha induced transcription of the target gene
CCL11 in human airway smooth muscle cells by phosphorylating the HAT p/CAF ... Studies using reporters, overexpression strategies, kinase-dead and HAT-defective mutants, and chromatin immunoprecipitation showed that PKCbetaII activation was not involved in NF-kappaB translocation, but facilitated
NF-kappaB mediated
CCL11 transcription by colocalizing with and phosphorylating p/CAF, and thereby acetylating histone H4 and promoting p65 association with the CCL11 promoter ... These data suggest a novel important biological role for PKCbetaIotaIota in
NF-kappaB mediated
CCL11 transcription by p/CAF activation and histone H4 acetylation
Jamaluddin et al., Arterioscler Thromb Vasc Biol 2009
:
Eotaxin also
increased the phosphorylation of Stat3 and nuclear translocation of
NF-kappaB in HCAECs
Waddell et al., J Immunol 2013
(Colitis, Ulcerative...) :
Intestinal
CCL11 and Eosinophilic Inflammation Is
Regulated by Myeloid Cell-Specific
RelA/p65 in Mice