Gene interactions and pathways from curated databases and text-mining

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ANGPT2 — WNK1

Text-mined interactions from Literome

Ruiz-Ortega et al., Circ Res 2000 : Ang II increased NF-kappaB DNA binding ( 5-fold, 10 ( - ) ( 9 ) mol/L at 1 hour ; electrophoretic mobility shift assay ), nuclear translocation of p50/p65 subunits, and cytosolic inhibitor kappaBalpha ( IkappaBalpha ) degradation
Zhang et al., Arterioscler Thromb Vasc Biol 2005 (Vasculitis) : Downregulation of RSK by small interfering RNA ( SiRNA ) in VSMCs was found to suppress Ang II-induced activation of NF-kappaB and p65 phosphorylation
Tsuchiya et al., Am J Physiol Endocrinol Metab 2006 (Obesity) : ANG II induced translocation of NF-kappaB p65 subunit from cytoplasm to nucleus by immunocytochemical study
Valente et al., J Mol Cell Cardiol 2012 (Cardiomegaly...) : Further, Ang-II induced IKK/p65 and JNK/c-Jun phosphorylation, NF-?B and AP-1 activation, and IL-18 and MMP-9 expression were also markedly attenuated in CIKS-null mice