◀ Back to STAT4

SOCS3 — STAT4

Pathways - manually collected, often from reviews:

• KEGG Jak-STAT signaling pathway: STAT1/STAT2/STAT3/STAT4/STAT5A/STAT5B/STAT6 → SOCS1/SOCS2/SOCS3/SOCS4/SOCS5/SOCS7 (gene expression, expression)
  

Text-mined interactions from Literome

Takatori et al., J Immunol 2005 : Importantly, the expression of suppressor of cytokine signaling (SOCS)3 , a potent inhibitor of IL-12 induced Stat4 activation, was decreased in Stat5a ( -/- ) CD4 ( + ) T cells
Tortorella et al., J Gerontol A Biol Sci Med Sci 2006 : These results indicate that a defective STAT4 activation, likely dependent on elevated SOCS3 levels, is involved in the impaired IL-12 dependent T-cell functions with aging
Inoue et al., Arerugi 2006 (Asthma...) : SOCS3 controls IL-12 dependent STAT4 activation and Th2 differentiation process