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INS — PC
Text-mined interactions from Literome
Fischer et al., Toxicol Appl Pharmacol 1999
:
Potential involvement of calcium, CaM kinase II, and MAP kinases in
PCB stimulated
insulin release from RINm5F cells ... The presence of extracellular calcium was required for
PCB induced
insulin release because removal of calcium from the medium attenuated the effect ... In addition, pretreatment of RINm5F cells with the calcium channel blocker verapamil also blocked
PCB induced
insulin release ...
PCB induced
insulin release was completely blocked by KN-93 ... The results of the present investigation suggest a role for calcium and CaM kinase II in
PCB induced
insulin release
Xu et al., Diabetologia 2008
(Insulinoma) :
The
role of
pyruvate carboxylase in
insulin secretion and proliferation in rat pancreatic beta cells