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Text-mined interactions from Literome
Wake et al., J Pharmacol Exp Ther 2009
:
AGE-2 and AGE-3
induced the expressions of ICAM-1, B7.1, B7.2, and CD40 on monocytes and the production of
interferon-gamma in PBMC
Takahashi et al., Eur J Pharmacol 2010
:
In a previous study, we found that glyceraldehyde derived
AGE ( AGE-2 ) and glycolaldehyde derived AGE ( AGE-3 ) at 100 microg/ml
induced the expressions of ICAM-1 and CD40 on monocytes and the production of
interferon (IFN)-gamma and tumor necrosis factor (TNF)-alpha in human peripheral blood mononuclear cells
Mori et al., Br J Pharmacol 2010
:
In addition, CIP inhibited AGE-2- and
AGE-3 induced expressions of ICAM-1, B7.1, B7.2 and CD40 in monocytes, the production of TNF-alpha and
IFN-gamma and lymphocyte proliferation in PBMC
Kyo et al., Phytomedicine 1998
:
Consequently,
AGE stimulated the proliferation of mouse spleen cells and the release of cytokines, such as IL-2, TNF-alpha and
IFN-gamma , increased NK activities, and enhanced phagocytosis of peritoneal macrophages
Imani et al., J Exp Med 1993
:
Under conditions of excessive AGE-protein and AGE lipid accumulation ( e.g., aging and diabetes ), enhanced production of
AGE induced
IFN-gamma may accelerate immune responses that contribute to tissue injury