◀ Back to IL21
GRB7 — IL21
Text-mined interactions from Literome
Lee et al., Phytother Res 2013
(Inflammation) :
GRb1 significantly
reduced the upregulation of tumor necrosis factor-a,
interleukin (IL)-1ß and IL-6 mRNA in the brain tissue at 4?h after LPS injection
Lindner et al., Cancer Res 2013
(Neoplasms) :
Mechanistic investigations into how
IL-21 induced
GrB expression in B cells to confer Breg function revealed a CD19 ( + ) CD38 ( + ) CD1d ( + ) IgM ( + ) CD147 ( + ) expression signature, along with expression of additional key regulatory molecules including IL-10, CD25, and indoleamine-2,3-dioxygenase ... Notably,
induction of
GrB by
IL-21 integrated signals mediated by surface immunoglobulin M ( B-cell receptor ) and Toll-like receptors, each of which were enhanced with expression of the B-cell marker CD5 ... Our findings show for the first time that
IL-21 induces
GrB ( + ) human Bregs