Gene interactions and pathways from curated databases and text-mining

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CD2 — EPHB2

Text-mined interactions from Literome

Martelli et al., Blood 2000 : Signaling via LAT ( linker for T-cell activation ) and Syk/ZAP70 is required for ERK activation and NFAT transcriptional activation following CD2 stimulation
Azriel-Tamir et al., J Biol Chem 2004 : We demonstrate that Ca2+ release, mediated by the ZnR, induces phosphorylation of ERK1/2 , which is highly metal-specific, mediated by physiological concentrations of extracellular Zn2+ but not by Cd2+ , Fe2+, Ni2+, or Mn2+
Boulay et al., J Immunol 2005 : These mutations abrogate CD2 induced phosphorylation and the ability of Dok-1 or Dok-2 to inhibit CD2 induced ERK1/2 and NFAT activation
Yang et al., J Immunol 2006 : The overexpression of CD2BP1 selectively attenuates phospholipase Cgamma1, ERK1/2 , and p38 phosphorylation without abrogating CD2 independent TCR stimulation
Rigon et al., Neurotoxicology 2008 : Cd(II) also stimulated the phosphorylation of ERK1/2 in a concentration dependent manner