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CD2 — EPHB2
Text-mined interactions from Literome
Martelli et al., Blood 2000
:
Signaling via LAT ( linker for T-cell activation ) and Syk/ZAP70 is required for
ERK activation and NFAT transcriptional activation following
CD2 stimulation
Azriel-Tamir et al., J Biol Chem 2004
:
We demonstrate that Ca2+ release, mediated by the ZnR, induces phosphorylation of
ERK1/2 , which is highly metal-specific,
mediated by physiological concentrations of extracellular Zn2+ but not by
Cd2+ , Fe2+, Ni2+, or Mn2+
Boulay et al., J Immunol 2005
:
These mutations abrogate
CD2 induced phosphorylation and the ability of Dok-1 or Dok-2 to inhibit CD2 induced
ERK1/2 and NFAT activation
Yang et al., J Immunol 2006
:
The overexpression of
CD2BP1 selectively
attenuates phospholipase Cgamma1,
ERK1/2 , and p38 phosphorylation without abrogating CD2 independent TCR stimulation
Rigon et al., Neurotoxicology 2008
:
Cd(II) also
stimulated the phosphorylation of
ERK1/2 in a concentration dependent manner