Tomimatsu et al., J Biol Chem 2007
:
In summary, we discovered a novel role for Ku70/80 in modulating ATM dependent ATR activation during DSB damage response and demonstrated that these proteins confer a protective effect against ATM independent ATR activation at later stages of the DSB damage response
Müller et al., J Cell Biol 2007
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DNA-PK is activated during replication stress and DNA-PK signaling is enhanced when ATR/ATM signaling is abrogated