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VEGFA — XRCC6

Text-mined interactions from Literome

Gama et al., Cell Death Differ 2009 : We found that VEGF inhibited cytosolic Ku70 degradation induced by apoptotic stress ... We found that VEGF stimulated nuclear translocation of Hdm2 in EC and efficiently inhibited Ku70 degradation
Tawa et al., Circ Res 2010 (Disease Models, Animal...) : These results demonstrate a novel molecular mechanism by which Rap1 and afadin regulate the VEGF- and S1P induced angiogenesis
Lakshmikanthan et al., Blood 2011 : Using ECs obtained from Rap1-deficient mice we demonstrate that Rap1b promotes VEGF-VEGFR2 kinase activation and regulates integrin activation ... Importantly, the Rap1b dependent VEGF-VEGFR2 activation is in part mediated via integrin a ( v ) ß ( 3 ) ... These results provide a novel insight into the role of Rap1 in VEGF signaling in ECs
Li et al., J Huazhong Univ Sci Technolog Med Sci 2011 : VEGF stimulated Rap1 activity, phosphorylation of ERK and Akt, cyclin D1 expression and cell proliferation were repressed in HUVECs overexpressing Rap1GAP as compared to empty vector transfected control