Gene interactions and pathways from curated databases and text-mining

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CNTF — PTPN11

Text-mined interactions from Literome

Ozawa et al., Mol Cell Neurosci 2004 : We demonstrated that STAT3 activation, but not SHP2 activation, is responsible for the CNTF/gp130 signaling that inhibits expression of Rhodopsin and its upstream activator, crx, in the retinal explants derived from P0 mice ( P0 retinal explants ), utilizing STAT3-deficient retina and electroporation of dominant negative form of STAT3 ( STAT3F )
Servidei et al., J Biol Chem 1998 : In this study, expression of an interfering mutant of SHP-2 in the neuroblastoma cell line NBFL increased CNTF induction of a vasoactive intestinal peptide (VIP) reporter gene, and in cultures of sympathetic neurons, it resulted in an up-regulation of endogenous VIP and substance P ( SP ) gene expression