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CXCR4 — FGF2

Text-mined interactions from Literome

Salcedo et al., Am J Pathol 1999 : Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells : In vivo neovascularization induced by stromal derived factor-1alpha
Sanders et al., J Neurosci Res 2000 (Acquired Immunodeficiency Syndrome) : These effects were dependent on the FGF receptor tyrosine kinase signaling pathway, because FGF induced effects on CXCR4 were blocked by the tyrosine kinase inhibitor, 5'-deoxy-5'methylthioadenosine, or by anti-FGF receptor antibody
Salcedo et al., Blood 2003 : Stimulation of vascular endothelial growth factor ( VEGF ) and basic fibroblast growth factor (bFGF) increases the expression of CXCR4 on endothelial cells, rendering these cells more responsive to stromal derived factor 1 (SDF-1), an angiogenic CXC chemokine and unique ligand for CXCR4
Salmaggi et al., J Neurooncol 2004 (Brain Neoplasms...) : CXCR4 was found in cells lines and primary cultures from malignant gliomas as well as in endothelial cells and was increased by vascular endothelial growth factor and basic fibroblast growth factor (bFGF)
Feil et al., Biochem Biophys Res Commun 1998 : Cytokine stimulation revealed that bFGF upregulates endothelial CXCR-4 expression, whereas TNF alpha downregulates endothelial CXCR-4 expression