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CRK — MAPKAPK5
Text-mined interactions from Literome
New et al., Mol Biol Cell 2003
:
Mutations in the docking groove on p38alpha/p38beta, or the p38 docking site in PRAK, disrupted the PRAK-p38 interaction and impaired the ability of p38alpha and p38beta to redistribute ectopically expressed PRAK, indicating that the location of
PRAK could be
controlled by its docking interaction with p38alpha and
p38beta ... The nuclear import of PRAK is independent from p38 activation, but the nuclear export requires
p38 mediated phosphorylation of
PRAK
New et al., EMBO J 1998
:
PRAK activity was
regulated by p38alpha and
p38beta both in vitro and in vivo and Thr182 was shown to be the regulatory phosphorylation site