◀ Back to NPM1

BAX — NPM1

Text-mined interactions from Literome

Lo et al., Hepatology 2013 (Carcinoma, Hepatocellular...) : Subcellular fractionation revealed that silencing of NPM expression greatly enhanced mitochondrial translocation and oligomerization of BAX in Huh7 and Mahlavu cells
Wang et al., Mol Cell Biol 2013 (Ischemia...) : Expression of a cytosol restricted NPM mutant ( NPM-dNLS ), but not a nucleus restricted NPM mutant, increased NPM-Bax complex formation, mitochondrial NPM and Bax accumulation, mitochondrial membrane injury, caspase 3 activation, and ischemia induced cell death ... Thus, NPM-Bax interaction enhances mitochondrial Bax accumulation, organelle injury, and cell death