Tian et al., J Endocrinol 2009
(Carcinoma...) :
The unliganded ERalpha upregulated LRP16 expression and enhanced LRP16 promoter activity in SKOV3 cells ; however, this induction was blocked by estrogen stimulation
Meng et al., BMC cell biology 2009
:
LRP16 is both an ERalpha target gene and an ERalpha coactivator, and plays a crucial role in ERalpha activation and proliferation of MCF-7 breast cancer cells