Gene interactions and pathways from curated databases and text-mining

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CDH17 — EGFR

Text-mined interactions from Literome

O'Keefe et al., Dev Biol 2007 : Egfr/Ras signaling regulates DE-cadherin/Shotgun localization to control vein morphogenesis in the Drosophila wing
Klessner et al., Mol Biol Cell 2009 : We previously showed that EGFR inhibition results in accumulation of the desmosomal cadherin , desmoglein 2 (Dsg2), at cell-cell interfaces accompanied by inhibition of matrix metalloprotease ( MMP ) -dependent shedding of the Dsg2 ectodomain and tyrosine phosphorylation of its cytoplasmic domain
Gan et al., Oncogene 2010 (MAP Kinase Signaling System...) : Knockdown of endogenous Snail also prevents EGFR mediated downregulation of E-cadherin , EMT and cell migration
Sakamoto et al., Cancer Sci 2012 (Stomach Neoplasms) : Liver-intestine cadherin induction by epidermal growth factor receptor is associated with intestinal differentiation of gastric cancer ... These results indicate that, in addition to the known intestinal transcription factor caudal type homeobox 2, EGFR activation induces LI-cadherin expression and participates in intestinal differentiation of GC