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HNF1A — IL4

Text-mined interactions from Literome

Maier et al., J Biol Chem 2011 : The down-regulation is largely due to the polarizing cytokine IL-4 because IL-4 alone is sufficient to substantially inhibit TCF-1 expression ... The IL-4 induced suppression of TCF-1 is mediated by STAT6, as shown by electrophoretic mobility shift assays, chromatin immunoprecipitation, and STAT6 knockdown experiments
Sharma et al., J Immunol 2012 : Generation of TCF1 and ß-catenin dependent memory-like CD8 thymocytes is non-cell-intrinsic and requires the expression of IL-4 and IL-4R