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FGFR2 — GATA4
Text-mined interactions from Literome
Yang et al., Biol Reprod 2011
:
Moreover, FGF signaling appears important for initiation of PE formation in blastocysts, presumably by lineage committal from NANOG positive epiblast cells, because chemical disruption of
FGFR kinase activity with PD173074
reduces GATA4 expression and increases NANOG expression
Chen et al., Dev Dyn 2012
:
Inhibition of
Fgfr2 activation by SU5402 in parthenotes
restored normal Nanog and
Gata4 levels without affecting Fgf3, indicating that Fgf3 is upstream of Fgfr2 activation