Gene interactions and pathways from curated databases and text-mining

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SAA2 — TNF

Text-mined interactions from Literome

Thorn et al., Amyloid 2002 : The Saa1 and Saa2 promoters are strongly induced by IL-6, with synergistic upregulation of Saa2, but not of Saa1, by IL-1 or TNF
Hagihara et al., Biochem Biophys Res Commun 2004 : Either IL-6 and IL-1beta or IL-6 and TNFalpha, but not IL-1beta and TNFalpha , induced the synergistic induction of SAA1 and SAA2 genes
Son et al., Endocrinology 2004 : Tumor necrosis factor-alpha induces serum amyloid A3 in mouse granulosa cells
Thorn et al., Scand J Immunol 2004 : Here, we examine the roles of TNF-alpha , interleukin-6 (IL-6) and GCs on the transcriptional regulation of the two human A-SAA genes ( SAA1 and SAA2 ) and show that these stimuli have different effects on the SAA1 and SAA2 promoters in HepG2 hepatoma and KB epithelial cell lines
Lee et al., Mol Pharmacol 2006 : We found that serum amyloid A stimulated the production of tumor necrosis factor (TNF)-alpha and interleukin (IL)-10, which are proinflammatory and anti-inflammatory cytokines, respectively, in human monocytes
Connolly et al., Arthritis Rheum 2012 (Arthritis, Rheumatoid...) : Acute-phase serum amyloid A regulates tumor necrosis factor a and matrix turnover and predicts disease progression in patients with inflammatory arthritis before and after biologic therapy
Ghezzi et al., Lymphokine Res 1988 : Dexamethasone modulation of LPS, IL-1, and TNF stimulated serum amyloid A synthesis in mice
Sipe et al., Lymphokine Res 1987 : Tumor necrosis factor/cachectin is a less potent inducer of serum amyloid A synthesis than interleukin 1