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SAA2 — TNF
Text-mined interactions from Literome
Thorn et al., Amyloid 2002
:
The Saa1 and
Saa2 promoters are strongly
induced by IL-6, with synergistic upregulation of Saa2, but not of Saa1, by IL-1 or
TNF
Hagihara et al., Biochem Biophys Res Commun 2004
:
Either IL-6 and IL-1beta or IL-6 and TNFalpha, but not IL-1beta and
TNFalpha ,
induced the synergistic induction of SAA1 and
SAA2 genes
Son et al., Endocrinology 2004
:
Tumor necrosis factor-alpha induces
serum amyloid A3 in mouse granulosa cells
Thorn et al., Scand J Immunol 2004
:
Here, we examine the
roles of
TNF-alpha , interleukin-6 (IL-6) and GCs on the transcriptional regulation of the two human A-SAA genes ( SAA1 and
SAA2 ) and show that these stimuli have different effects on the SAA1 and SAA2 promoters in HepG2 hepatoma and KB epithelial cell lines
Lee et al., Mol Pharmacol 2006
:
We found that
serum amyloid A stimulated the production of
tumor necrosis factor (TNF)-alpha and interleukin (IL)-10, which are proinflammatory and anti-inflammatory cytokines, respectively, in human monocytes
Connolly et al., Arthritis Rheum 2012
(Arthritis, Rheumatoid...) :
Acute-phase
serum amyloid A regulates
tumor necrosis factor a and matrix turnover and predicts disease progression in patients with inflammatory arthritis before and after biologic therapy
Ghezzi et al., Lymphokine Res 1988
:
Dexamethasone modulation of LPS, IL-1, and
TNF stimulated
serum amyloid A synthesis in mice
Sipe et al., Lymphokine Res 1987
:
Tumor necrosis factor/cachectin is a less potent
inducer of
serum amyloid A synthesis than interleukin 1