Fukushima et al., Bone 2005
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IL-1alpha induced tartrate-resistant acid phosphatase positive ( TRAP+ ) cell formation in a dose dependent manner
Jules et al., J Biol Chem 2012
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Here we show that although IL-1 can not activate the expression of the osteoclast genes encoding matrix metalloproteinase 9, cathepsin K, tartrate-resistant acid phosphatase , and carbonic anhydrase II in bone marrow macrophages ( BMMs ), RANKL renders these osteoclast genes responsive to IL-1